Dr. Alexis Combes is an Associate Professor in the Department of Pathology at UC San Francisco. He is a formally trained immunologist and cell biologist with specific training and expertise in elucidating mechanisms of immune pathogenesis. His current research employs a systems immunology approach to discover and dissect recurring patterns of the immune system, or immune archetypes, in health and disease with the aim of guiding the development of relevant, precision immunotherapies. He also serves as the Director of the Disease to Biology (D2B) CoLab, which is a collaboration-based research lab at UCSF that focuses on profiling the immune system in both diseased patients and healthy individuals using cutting-edge technologies to better understand the immunological context of different diseases.

Dr. Combes received his Ph.D. in Immunology from Aix-Marseille University with a focus on cellular signaling during dendritic cell activation. He completed his postdoctoral training at the University of California, San Francisco, under the mentorship of Dr. Matthew Krummel, where he utilized immune monitoring and high-dimensional single-cell technologies to show the existence of archetypal organization of the immune system in tumors.